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Substrate sequestration by a proteolytically inactive Lon mutant

Lon protein of Escherichia coli is an ATP-dependent protease responsible for the rapid turnover of both abnormal and naturally unstable proteins, including SulA, a cell division inhibitor made after DNA damage, and RcsA, a positive regulator of transcription. Lon is a multimer of identical 94-kDa su...

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Bibliographic Details
Main Authors: Van Melderen, Laurence, Gottesman, Susan
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC26836/
https://ncbi.nlm.nih.gov/pubmed/10339542
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