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MAPK/ERK1/2 and PI3-kinase signalling pathways are required for vitreous-induced lens fibre cell differentiation

Lens epithelial cells withdraw from the cell cycle to differentiate into secondary fibre cells in response to vitreal factors. Fibroblast growth factor (FGF) in the vitreous has been shown to induce lens fibre differentiation in vivo and in vitro through the activation of defined intracellular signa...

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Hlavní autoři: Wang, Qian, Stump, Richard, McAvoy, John W, Lovicu, Frank J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683269/
https://ncbi.nlm.nih.gov/pubmed/18938158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.08.023
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