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p75 reduces β-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model

β-Amyloid (Aβ) has adverse effects on brain cells, but little is known about its effects on the peripheral nervous system in Alzheimer's disease (AD). Several lines of in vitro evidence suggest that the neurotrophin receptor p75 mediates or exacerbates Aβ-induced neurotoxicity. Here, we show th...

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Main Authors: Bengoechea, Tasha G., Chen, Zhijiang, O'Leary, Debra A., Masliah, Eliezer, Lee, Kuo-Fen
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683130/
https://ncbi.nlm.nih.gov/pubmed/19416837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901533106
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