p75 reduces β-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model

β-Amyloid (Aβ) has adverse effects on brain cells, but little is known about its effects on the peripheral nervous system in Alzheimer's disease (AD). Several lines of in vitro evidence suggest that the neurotrophin receptor p75 mediates or exacerbates Aβ-induced neurotoxicity. Here, we show th...

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Bibliographic Details
Main Authors: Bengoechea, Tasha G., Chen, Zhijiang, O'Leary, Debra A., Masliah, Eliezer, Lee, Kuo-Fen
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683130/
https://ncbi.nlm.nih.gov/pubmed/19416837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901533106
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