Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella

Bacteria have developed an exclusive signal transduction system involving multiple diguanylate cyclase and phosphodiesterase domain-containing proteins (GGDEF and EAL/HD-GYP, respectively) that modulate the levels of the same diffusible molecule, 3′-5′-cyclic diguanylic acid (c-di-GMP), to transmit...

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Bibliographic Details
Main Authors: Solano, Cristina, García, Begoña, Latasa, Cristina, Toledo-Arana, Alejandro, Zorraquino, Violeta, Valle, Jaione, Casals, Joan, Pedroso, Enrique, Lasa, Iñigo
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683120/
https://ncbi.nlm.nih.gov/pubmed/19416883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812573106
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