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Schizosaccharomyces pombe Rtf2 mediates site-specific replication termination by inhibiting replication restart

Here, we identify a phylogenetically conserved Schizosaccharomyces pombe factor, named Rtf2, as a key requirement for efficient replication termination at the site-specific replication barrier RTS1. We show that Rtf2, a proliferating cell nuclear antigen-interacting protein, promotes termination at...

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Bibliografiske detaljer
Main Authors: Inagawa, Takabumi, Yamada-Inagawa, Tomoko, Eydmann, Trevor, Mian, I. Saira, Wang, Teresa S., Dalgaard, Jacob Z.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683088/
https://ncbi.nlm.nih.gov/pubmed/19416828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812323106
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