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Closely linked cis-acting modifier of expansion of the CGG repeat in high risk FMR1 haplotypes

In its expanded form, the fragile X triplet repeat at Xq27.3 gives rise to the most common form of inherited mental retardation, fragile X syndrome. This high population frequency persists despite strong selective pressure against mutation-bearing chromosomes. Males carrying the full mutation rarely...

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Détails bibliographiques
Auteurs principaux: Ennis, S, Murray, A, Brightwell, G, Morton, NE, Jacobs, PA
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683060/
https://ncbi.nlm.nih.gov/pubmed/17674408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.20600
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