Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster

Long-range regulatory elements and higher-order chromatin structure coordinate the expression of multiple genes in cluster, and CTCF/cohesin-mediated chromatin insulator may be a key in this regulation. The human apolipoprotein (APO) A1/C3/A4/A5 gene region, whose alterations increase the risk of dy...

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Detalhes bibliográficos
Main Authors: Mishiro, Tsuyoshi, Ishihara, Ko, Hino, Shinjiro, Tsutsumi, Shuichi, Aburatani, Hiroyuki, Shirahige, Katsuhiko, Kinoshita, Yoshikazu, Nakao, Mitsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683055/
https://ncbi.nlm.nih.gov/pubmed/19322193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.81
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