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Alteration of TLR3 pathways by glucocorticoids may be responsible for immunosusceptibility of human corneal epithelial cells to viral infections

Purpose: The toll-like receptor 3 (TLR3) recognizes viral double-stranded RNA and its synthetic analog polyriboinosinic-polyribocytidylic acid (poly(I:C)), and the activation of TLR3 is known to induce the production of type I interferon (IFN) and inflammatory cytokines/chemokines. The purpose of th...

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Bibliografiske detaljer
Main Authors: Hara, Yuko, Shiraishi, Atsushi, Kobayashi, Takeshi, Kadota, Yuko, Shirakata, Yuji, Hashimoto, Koji, Ohashi, Yuichi
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683030/
https://ncbi.nlm.nih.gov/pubmed/19452017
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