Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis

Anthrolysin O (ALO) is a pore-forming, cholesterol-dependent cytolysin (CDC) secreted by Bacillus anthracis, the etiologic agent for anthrax. Growing evidence suggests the involvement of ALO in anthrax pathogenesis. Here, we show that the apical application of ALO decreases the barrier function of h...

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Detalhes bibliográficos
Main Authors: Bourdeau, Raymond W., Malito, Enrico, Chenal, Alexandre, Bishop, Brian L., Musch, Mark W., Villereal, Mitch L., Chang, Eugene B., Mosser, Elise M., Rest, Richard F., Tang, Wei-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682912/
https://ncbi.nlm.nih.gov/pubmed/19307185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807631200
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