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Four-electron Reduction of Dioxygen by a Multicopper Oxidase, CueO, and Roles of Asp(112) and Glu(506) Located Adjacent to the Trinuclear Copper Center

The mechanism of the four-electron reduction of dioxygen by a multicopper oxidase, CueO, was studied based on reactions of single and double mutants with Cys(500), a type I copper ligand, and the noncoordinating Asp(112) and Glu(506), which form hydrogen bonds with the trinuclear copper center direc...

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Detalhes bibliográficos
Main Authors: Kataoka, Kunishige, Sugiyama, Ryosuke, Hirota, Shun, Inoue, Megumi, Urata, Kanae, Minagawa, Yoichi, Seo, Daisuke, Sakurai, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682889/
https://ncbi.nlm.nih.gov/pubmed/19297322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808468200
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