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Four-electron Reduction of Dioxygen by a Multicopper Oxidase, CueO, and Roles of Asp(112) and Glu(506) Located Adjacent to the Trinuclear Copper Center
The mechanism of the four-electron reduction of dioxygen by a multicopper oxidase, CueO, was studied based on reactions of single and double mutants with Cys(500), a type I copper ligand, and the noncoordinating Asp(112) and Glu(506), which form hydrogen bonds with the trinuclear copper center direc...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682889/ https://ncbi.nlm.nih.gov/pubmed/19297322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808468200 |
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