Carregant...

Coordinated Activation of the Origin Licensing Factor CDC6 and CDK2 in Resting Human Fibroblasts Expressing SV40 Small T Antigen and Cyclin E

We have previously shown that SV40 small t antigen (st) cooperates with deregulated cyclin E to activate CDK2 and bypass quiescence in normal human fibroblasts (NHF). Here we show that st expression in serum-starved and density-arrested NHF specifically induces up-regulation and loading of CDC6 onto...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Sotillo, Elena, Garriga, Judit, Padgaonkar, Amol, Kurimchak, Alison, Cook, Jeanette Gowen, Graña, Xavier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682861/
https://ncbi.nlm.nih.gov/pubmed/19321444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900687200
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!