c-Jun NH(2)-Terminal Kinase Activity in Subcutaneous Adipose Tissue but Not Nuclear Factor-κB Activity in Peripheral Blood Mononuclear Cells Is an Independent Determinant of Insulin Resistance in Healthy Individuals

OBJECTIVE: Chronic low-grade activation of the immune system (CLAIS) predicts type 2 diabetes via a decrease in insulin sensitivity. Our study investigated potential relationships between nuclear factor-κB (NF-κB) and c-Jun NH(2)-terminal kinase (JNK) pathways—two pathways proposed as the link betwe...

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Detalhes bibliográficos
Main Authors: Sourris, Karly C., Lyons, Jasmine G., de Courten, Maximilian P.J., Dougherty, Sonia L., Henstridge, Darren C., Cooper, Mark E., Hage, Michelle, Dart, Anthony, Kingwell, Bronwyn A., Forbes, Josephine M., de Courten, Barbora
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682665/
https://ncbi.nlm.nih.gov/pubmed/19258436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1725
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