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Sox17 Promotes Cell Cycle Progression and Inhibits TGF-β/Smad3 Signaling to Initiate Progenitor Cell Behavior in the Respiratory Epithelium

The Sry-related high mobility group box transcription factor Sox17 is required for diverse developmental processes including endoderm formation, vascular development, and fetal hematopoietic stem cell maintenance. Expression of Sox17 in mature respiratory epithelial cells causes proliferation and li...

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Autori principali: Lange, Alexander W., Keiser, Angela R., Wells, James M., Zorn, Aaron M., Whitsett, Jeffrey A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682659/
https://ncbi.nlm.nih.gov/pubmed/19479035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005711
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