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Tat-SF1 Is Not Required for Tat Transactivation but Does Regulate the Relative Levels of Unspliced and Spliced HIV-1 RNAs

BACKGROUND: HIV-1 relies on several host proteins for productive viral transcription. HIV-1 Tat-specific factor 1 (Tat-SF1) is among these cofactors that were identified by in vitro reconstituted transcription reactions with immunodepleted nuclear extracts. At the onset of this work, the prevailing...

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Detalhes bibliográficos
Main Authors: Miller, Heather B., Saunders, Kevin O., Tomaras, Georgia D., Garcia-Blanco, Mariano A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682658/
https://ncbi.nlm.nih.gov/pubmed/19479034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005710
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