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Cdc14 Inhibition by the Spindle Assembly Checkpoint Prevents Unscheduled Centrosome Separation in Budding Yeast

The spindle assembly checkpoint (SAC) is an evolutionarily conserved surveillance mechanism that delays anaphase onset and mitotic exit in response to the lack of kinetochore attachment. The target of the SAC is the E3 ubiquitin ligase anaphase-promoting complex (APC) bound to its Cdc20 activator. T...

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Detalhes bibliográficos
Main Authors: Chiroli, Elena, Rancati, Giulia, Catusi, Ilaria, Lucchini, Giovanna, Piatti, Simonetta
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682603/
https://ncbi.nlm.nih.gov/pubmed/19339280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-11-1150
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