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Reexamining microRNA Site Accessibility in Drosophila: A Population Genomics Study

Kertesz et al. (Nature Genetics 2008) described PITA, a miRNA target prediction algorithm based on hybridization energy and site accessibility. In this note, we used a population genomics approach to reexamine their data and found that the PITA algorithm had lower specificity than methods based on e...

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Библиографические подробности
Главные авторы: Chen, Kevin, Maaskola, Jonas, Siegal, Mark L., Rajewsky, Nikolaus
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682560/
https://ncbi.nlm.nih.gov/pubmed/19478854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005681
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