Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8(+) T Lymphocytes

Telomerase reverse transcribes telomere DNA onto the ends of linear chromosomes and retards cellular aging. In contrast to most normal somatic cells, which show little or no telomerase activity, immune cells up-regulate telomerase in concert with activation. Nevertheless, during aging and chronic HI...

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Autores principales: Fauce, Steven Russell, Jamieson, Beth D., Chin, Allison C., Mitsuyasu, Ronald T., Parish, Stan T., Ng, Hwee L., Kitchen, Christina M. Ramirez, Yang, Otto O., Harley, Calvin B., Effros, Rita B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682219/
https://ncbi.nlm.nih.gov/pubmed/18981163
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