c-Myc and Rel/NF-κB Are the Two Master Transcriptional Systems Activated in the Latency III Program of Epstein-Barr Virus-Immortalized B Cells

The Epstein-Barr virus (EBV) latency III program imposed by EBNA2 and LMP1 is directly responsible for immortalization of B cells in vitro and is thought to mediate most immunodeficiency-related posttransplant lymphoproliferative diseases in vivo. To answer the question whether and how this prolifer...

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Detalhes bibliográficos
Main Authors: Faumont, Nathalie, Durand-Panteix, Stéphanie, Schlee, Martin, Grömminger, Sebastian, Schuhmacher, Marino, Hölzel, Michael, Laux, Gerhard, Mailhammer, Reinhard, Rosenwald, Andreas, Staudt, Louis M., Bornkamm, Georg W., Feuillard, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682111/
https://ncbi.nlm.nih.gov/pubmed/19264782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02264-08
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