Geminivirus AL2 and L2 Proteins Suppress Transcriptional Gene Silencing and Cause Genome-Wide Reductions in Cytosine Methylation

Geminiviruses replicate single-stranded DNA genomes through double-stranded intermediates that associate with cellular histone proteins. Unlike RNA viruses, they are subject to RNA-directed methylation pathways that target viral chromatin and likely lead to transcriptional gene silencing (TGS). Here...

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Bibliographic Details
Main Authors: Buchmann, R. Cody, Asad, Shaheen, Wolf, Jamie N., Mohannath, Gireesha, Bisaro, David M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682068/
https://ncbi.nlm.nih.gov/pubmed/19279102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01771-08
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