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Mutational Analysis of the Sir3 BAH Domain Reveals Multiple Points of Interaction with Nucleosomes

Sir3, a component of the transcriptional silencing complex in the yeast Saccharomyces cerevisiae, has an N-terminal BAH domain that is crucial for the protein's silencing function. Previous work has shown that the N-terminal alanine residue of Sir3 (Ala2) and its acetylation play an important r...

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Autors principals: Sampath, Vinaya, Yuan, Peihua, Wang, Isabel X., Prugar, Evelyn, van Leeuwen, Fred, Sternglanz, Rolf
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682052/
https://ncbi.nlm.nih.gov/pubmed/19273586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01682-08
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