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Normal Function of the Yeast TOR Pathway Requires the Type 2C Protein Phosphatase Ptc1

Yeast ptc1 mutants are rapamycin and caffeine sensitive, suggesting a functional connection between Ptc1 and the TOR pathway that is not shared by most members of the type 2C phosphatase family. Genome-wide profiling revealed that the ptc1 mutation largely attenuates the transcriptional response to...

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Bibliografske podrobnosti
Main Authors: González, Asier, Ruiz, Amparo, Casamayor, Antonio, Ariño, Joaquín
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682041/
https://ncbi.nlm.nih.gov/pubmed/19273591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01740-08
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