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Direct detection of Mycobacterium tuberculosis in clinical specimens by DNA amplification.

A polymerase chain reaction assay was developed for the amplification of a 336-bp repetitive fragment in the chromosome of Mycobacterium tuberculosis. The assay is specific for M. tuberculosis and can be used to detect the amount of DNA present in less than 10 organisms. It was used to demonstrate M...

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Bibliographic Details
Main Authors: De Wit, D, Steyn, L, Shoemaker, S, Sogin, M
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC268202/
https://ncbi.nlm.nih.gov/pubmed/2123884
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