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Dimerization and a Novel Tax Speckled Structure Localization Signal Are Required for Tax Nuclear Localization

The human T-cell leukemia virus type 1 oncoprotein Tax has pleiotropic activities, a subset of which likely leads to immortalization of T cells. Tax is expressed and known to function in both the cell nucleus and the cytoplasm. Tax has defined nuclear localization (NLS) and nuclear export signals th...

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Main Authors: Fryrear, Kimberly A., Durkin, Sarah S., Gupta, Saurabh K., Tiedebohl, Jessica B., Semmes, O. John
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681966/
https://ncbi.nlm.nih.gov/pubmed/19321601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-09
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