CCR5- and CXCR4-Tropic Subtype C Human Immunodeficiency Virus Type 1 Isolates Have a Lower Level of Pathogenic Fitness than Other Dominant Group M Subtypes: Implications for the Epidemic

Human immunodeficiency virus type 1 (HIV-1) subtype C is the dominant subtype globally, due largely to the incidence of subtype C infections in sub-Saharan Africa and east Asia. We compared the relative replicative fitness (ex vivo) of the major (M) group of HIV-1 subtypes A, B, C, D, and CRF01_AE a...

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Bibliographic Details
Main Authors: Abraha, Awet, Nankya, Immaculate L., Gibson, Richard, Demers, Korey, Tebit, Denis M., Johnston, Elizabeth, Katzenstein, David, Siddiqui, Asna, Herrera, Carolina, Fischetti, Lucia, Shattock, Robin J., Arts, Eric J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Genetic Diversity and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681953/
https://ncbi.nlm.nih.gov/pubmed/19297481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02051-08
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