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Influenza A Virus Lacking M2 Protein as a Live Attenuated Vaccine
Mutant influenza virus that lacks the transmembrane and cytoplasmic tail domains of M2 (M2 knockout [M2KO]) is attenuated in both cell culture and mice. Here, we examined the potency of M2KO influenza virus as a live attenuated influenza vaccine. M2KO virus grew as efficiently as the wild-type virus...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681926/ https://ncbi.nlm.nih.gov/pubmed/19321619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00450-09 |
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