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Identification of the Asparagine Synthase Responsible for d-Asp Amidation in the Lactococcus lactis Peptidoglycan Interpeptide Crossbridge

We show that in Lactococcus lactis, the gene asnH encodes the asparagine synthase involved in amidation of d-Asp present in peptidoglycan side chains and crossbridges. The level of d-Asp amidation in peptidoglycan has a strong effect on the sensitivity of bacteria to endogenous autolysins and to the...

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Auteurs principaux: Veiga, Patrick, Erkelenz, Michael, Bernard, Elvis, Courtin, Pascal, Kulakauskas, Saulius, Chapot-Chartier, Marie-Pierre
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681893/
https://ncbi.nlm.nih.gov/pubmed/19329637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00126-09
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