Modulation of Toll-Like Receptor 2 (TLR2) and TLR4 Responses by Aspergillus fumigatus

Toll-like receptor (TLR)-based signaling pathways in the host may be modulated by pathogens during the course of infection. We describe a novel immunomodulatory mechanism in which Aspergillus fumigatus conidia induce attenuation of TLR2- and TLR4-mediated interleukin (IL)-6 and IL-1β proinflammatory...

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Detalhes bibliográficos
Main Authors: Chai, Louis Y. A., Kullberg, Bart Jan, Vonk, Alieke G., Warris, Adilia, Cambi, Alessandra, Latgé, Jean-Paul, Joosten, Leo A. B., van der Meer, Jos W. M., Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681752/
https://ncbi.nlm.nih.gov/pubmed/19204090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01455-08
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