Genetically Modified L3,7 and L2 Lipooligosaccharides from Neisseria meningitidis Serogroup B Confer a Broad Cross-Bactericidal Response

Currently available Neisseria meningitidis serogroup B (MenB) vaccines are based on outer membrane vesicles (OMVs) that are obtained from wild-type strains. They are purified with the aim of decreasing the lipooligosaccharide (LOS) content and hence reduce the reactogenicity of the vaccine even thou...

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Detalhes bibliográficos
Main Authors: Weynants, V., Denoël, P., Devos, N., Janssens, D., Feron, C., Goraj, K., Momin, P., Monnom, D., Tans, C., Vandercammen, A., Wauters, F., Poolman, Jan T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681751/
https://ncbi.nlm.nih.gov/pubmed/19289516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01108-08
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