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Tolevamer Is Not Efficacious in the Neutralization of Cytotoxin in a Human Gut Model of Clostridium difficile Infection

The efficacy of tolevamer, a nonantimicrobial styrene derivative toxin-binding agent, in treating simulated Clostridium difficile infection in an in vitro human gut model was investigated. Tolevamer reduced neither the duration nor magnitude of cytotoxin activity by C. difficile, reflecting poor eff...

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מידע ביבליוגרפי
Main Authors: Baines, Simon D., Freeman, Jane, Wilcox, Mark H.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681510/
https://ncbi.nlm.nih.gov/pubmed/19223641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01085-08
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