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Transient Anti-CD40L Co-stimulation Blockade Prevents Immune Responses Against Human Bullous Pemphigoid Antigen 2: Implications For Gene Therapy
Skin grafts from mice expressing hBPAG2 in epidermal basement membrane elicit hBPAG2-specific IgG and graft loss in wild type (Wt) recipients. Graft loss was dependent upon CD4+ T cells and correlated with the production and tissue deposition of hBPAG2-specific IgG. To explore the role of CD40/CD40...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681490/ https://ncbi.nlm.nih.gov/pubmed/19037236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.364 |
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