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Serum Half-Life of Pituitary Gonadotropins Is Decreased by Sulfonation and Increased by Sialylation in Women

Context: The gonadotropins are secreted from the human pituitary as spectra of isoforms with different degrees of sulfonation and sialylation of the oligosaccharides, modifications suspected to determine their half-lives in the circulation. Objectives: Our objectives were to determine the isoform co...

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Autors principals: Wide, Leif, Eriksson, Karin, Sluss, Patrick M., Hall, Janet E.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681272/
https://ncbi.nlm.nih.gov/pubmed/19116233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-2070
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