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A Robust Platform for the Synthesis of New Tetracycline Antibiotics
Tetracyclines and tetracycline analogs are prepared by a convergent, single-step Michael–Claisen condensation of the AB precursors 1 or 2 with D-ring precursors of wide structural variability, followed by removal of protective groups (typically in two steps). A number of procedural variants of the k...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681267/ https://ncbi.nlm.nih.gov/pubmed/19053822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806629e |
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