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Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection

Membrane complement inhibitors (CD46, CD55 and CD59) are upregulated in some human cancers indicating that they play a role in immune evasion. We investigated complement inhibitor expression in bladder cancer and examined the hypothesis that selective pressure of an antibody response (anti-MUC1) res...

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Autori principali: Varela, Juan Carlos, Atkinson, Carl, Woolson, Robert, Keane, Thomas E., Tomlinson, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681224/
https://ncbi.nlm.nih.gov/pubmed/18561323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23676
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