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TRPC5/Orai1/STIM1-dependent Store-operated Entry of Ca(2+) Is Linked to Degranulation in a Rat Mast Cell Line

Degranulation of mast cells in response to antigen (Ag) or the calcium mobilizing agent, thapsigargin, is dependent on emptying of intracellular stores of Ca(2+) and the ensuing influx of external Ca(2+), also referred to as store-operated calcium entry (SOCE). However, it is unlikely that the calci...

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Bibliographic Details
Main Authors: Ma, Hong-Tao, Peng, Ze, Hiragun, Takaaki, Iwaki, Shoko, Gilfillan, Alasdair M., Beaven, Michael A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681184/
https://ncbi.nlm.nih.gov/pubmed/18250430
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