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The Effect of Intravenous Lidocaine on Brain Activation During Non-Noxious and Acute Noxious Stimulation of the Forepaw: A Functional Magnetic Resonance Imaging Study in the Rat

BACKGROUND: Lidocaine can alleviate acute as well as chronic neuropathic pain at very low plasma concentrations in humans and laboratory animals. The mechanism(s) underlying lidocaine’s analgesic effect when administered systemically is poorly understood but clearly not related to interruption of pe...

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Detalhes bibliográficos
Main Authors: Luo, Zhongchi, Yu, Mei, Smith, S. David, Kritzer, Mary, Du, Congwu, Ma, Yu, Volkow, Nora D., Glass, Peter S., Benveniste, Helene
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681082/
https://ncbi.nlm.nih.gov/pubmed/19095870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ane.0b013e31818e0d34
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