HIV-1 RNA Dysregulates the Natural TLR Response to Subclinical Endotoxemia in Kenyan Female Sex-Workers

BACKGROUND: Subclinical endotoxemia has been reported in HIV-1 infected persons and may drive systemic immune activation and pathogenesis. Proinflammatory responsiveness to endotoxin (LPS) is mediated by Toll-like receptor 4 (TLR4). We therefore examined the association between plasma LPS levels, HI...

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Detalhes bibliográficos
Main Authors: Lester, Richard T., Yao, Xiao-Dan, Ball, T. Blake, McKinnon, Lyle R., Omange, Were R., Kaul, Rupert, Wachihi, Charles, Jaoko, Walter, Rosenthal, Kenneth L., Plummer, Francis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680984/
https://ncbi.nlm.nih.gov/pubmed/19461969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005644
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