Autonomous Tetramerization Domains in the Glycan-binding Receptors DC-SIGN and DC-SIGNR

Multivalent binding of glycans on pathogens and on mammalian cells by the receptors DC-SIGN (CD209) and DC-SIGNR (L-SIGN, CD299) is dependent on correct disposition of the C-type carbohydrate-recognition domains projected at the C-terminal ends of necks at the cell surface. In the work reported here...

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Main Authors: Yu, Quan D., Oldring, Asa P., Powlesland, Alex S., Tso, Cynthia K.W., Yang, Chunxuan, Drickamer, Kurt, Taylor, Maureen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680971/
https://ncbi.nlm.nih.gov/pubmed/19249311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.02.046
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