A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice

Chlamydia trachomatis genome is predicted to encode a type III secretion system consisting of more than forty open reading frames (ORFs). To test whether these ORFs are expressed and immunogenic during chlamydial infection in humans, we expressed 55 chlamydial ORFs covering all putative type III sec...

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Autori principali: Wang, Jie, Chen, Lili, Chen, Fan, Zhang, Xiaoyun, Zhang, Yingqian, Baseman, Joel, Perdue, Sondra, Yeh, I-Tien, Shain, Rochelle, Holland, Martin, Bailey, Robin, Mabey, David, Yu, Ping, Zhong, Guangming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680781/
https://ncbi.nlm.nih.gov/pubmed/19428908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.02.095
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