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Aldehyde Dehydrogenase-2 Transgene Ameliorates Chronic Alcohol Ingestion-Induced Apoptosis in Cerebral Cortex

Chronic intake of alcohol results in multiple organ damage including brain. This study was designed to examine the impact of facilitated acetaldehyde breakdown via transgenic overexpression of mitochondrial aldehyde dehydrogenase-2 (ALDH2) on alcohol-induced cerebral cortical injury. ALDH2 transgeni...

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Main Authors: Ren, Jun, Babcock, Sara A., Li, Qun, Huff, Anna F., Li, Shi-Yan, Doser, Thomas A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680775/
https://ncbi.nlm.nih.gov/pubmed/19429258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2009.02.019
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