Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells

The centrosome directs chromosomal migration by a complex process of tubulin-chromatin binding. In this contribution centrosomal abnormalities, including centrosomal amplification, were explored in Chinese Hamster Ovary (CHO) and Normal Human Mammary Epithelial (NHMEC) cells exposed to the antiretro...

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Main Authors: Borojerdi, Jennifer P., Ming, Jessica, Cooch, Catherine, Ward, Yvona, Semino-Mora, Cristina, Yu, Mia, Braun, Hannan M., Taylor, Barbara J., Poirier, Miriam C., Olivero, Ofelia A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680773/
https://ncbi.nlm.nih.gov/pubmed/19427513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.03.004
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