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Structure-based discovery of dengue virus protease inhibitors
Dengue virus belongs to the family Flaviviridae and is a major emerging pathogen for which the development of vaccines and antiviral therapy has seen little success. The NS3 viral protease is a potential target for antiviral drugs since it is required for virus replication. The goal of this study wa...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2009
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680748/ https://ncbi.nlm.nih.gov/pubmed/19428601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.02.190 |
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