Injectable Peramivir Mitigates Disease and Promotes Survival in Ferrets and Mice Infected with the Highly Virulent Influenza Virus, A/Vietnam/1203/04 (H5N1)

The post-exposure therapeutic efficacy of injectable peramivir against highly pathogenic avian influenza type A H5N1 was evaluated in mice and in ferrets. Seventy to eighty percent of the H5N1-infected peramivir treated mice, and 70% in the oseltamivir treated mice survived the 15-day study period,...

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Detalhes bibliográficos
Main Authors: Yun, Nadezhda E., Linde, Nathaniel S., Zacks, Michele A., Barr, Ian G., Hurt, Aeron C., Smith, Jeanon N., Dziuba, Natallia, Holbrook, Michael R., Zhang, Lifang, Kilpatrick, John M., Arnold, C. Shane, Paessler, Slobodan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680697/
https://ncbi.nlm.nih.gov/pubmed/18234269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.12.029
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