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Structural Evidence for Common Ancestry of the Nuclear Pore Complex and Vesicle Coats

Nuclear pore complexes (NPCs) facilitate nucleocytoplasmic transport. These massive assemblies comprise an eight-fold symmetric scaffold of architectural proteins and central-channel phenylalanine-glycine-repeat proteins forming the transport barrier. We determined the Nup85•Seh1 structure, a module...

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Autores principales: Brohawn, Stephen G., Leksa, Nina C., Spear, Eric D., Rajashankar, Kanagalaghatta R., Schwartz, Thomas U.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680690/
https://ncbi.nlm.nih.gov/pubmed/18974315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1165886
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