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Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

Many risk genes interact synergistically to produce schizophrenia and many neurotransmitter interactions have been implicated. We have developed a circuit-based framework for understanding gene and neurotransmitter interactions. NMDAR hypofunction has been implicated in schizophrenia because NMDAR a...

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Detalhes bibliográficos
Main Authors: Lisman, John E., Coyle, Joseph T., Green, Robert W., Javitt, Daniel C., Benes, Francine M., Heckers, Stephan, Grace, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680493/
https://ncbi.nlm.nih.gov/pubmed/18395805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2008.02.005
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