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Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow

We have devised an ex vivo culture system which generates large numbers of eosinophils at high purity (>90%) from unselected mouse bone marrow progenitors. In response to four days of culture with recombinant mouse (rm)FLT3-L and rmSCF followed by rmIL-5 alone thereafter, the resulting bone-marro...

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Detalhes bibliográficos
Main Authors: Dyer, Kimberly D., Moser, Jennifer M., Czapiga, Meggan, Siegel, Steven J., Percopo, Caroline M., Rosenberg, Helene F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680436/
https://ncbi.nlm.nih.gov/pubmed/18768855
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