Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells

BACKGROUND: Small noncoding RNAs (ncRNAs), including short interfering RNAs (siRNAs) and microRNAs (miRNAs), can silence genes at the transcriptional, post-transcriptional or translational level [1,2]. RESULTS: Here, we show that microRNA-10a (miR-10a) targets a homologous DNA region in the promoter...

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Bibliografiske detaljer
Main Authors: Tan, Yuliang, Zhang, Bo, Wu, Tao, Skogerbø, Geir, Zhu, Xiaopeng, Guo, Xiangqian, He, Shunmin, Chen, Runsheng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680403/
https://ncbi.nlm.nih.gov/pubmed/19232136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-10-12
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