Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling

The cardiac extracellular matrix is a dynamic structural support network that is both influenced by, and a regulator of, pathological remodeling and hypertrophic growth. In response to pathologic insults the adult heart re-expresses the secreted extracellular matrix protein periostin (Pn). Here we s...

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Autori principali: Oka, Toru, Xu, Jian, Kaiser, Robert A., Melendez, Jaime, Hambleton, Michael, Sargent, Michelle A., Lorts, Angela, Brunskill, Eric W., Dorn, Gerald W., Conway, Simon J., Aronow, Bruce J., Robbins, Jeffrey, Molkentin, Jeffery D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680305/
https://ncbi.nlm.nih.gov/pubmed/17569887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.149047
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