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The 83-kilodalton antigen of Borrelia burgdorferi which stimulates immunoglobulin M (IgM) and IgG responses in infected hosts is expressed by a chromosomal gene.

We report the cloning and characterization of a chromosomal gene from Borrelia burgdorferi expressing an 83-kilodalton protein antigen in Escherichia coli. The antigen reacted strongly with antisera from two human Lyme disease patients. The chromosomal gene was expressed in a 6.5-kilobase-pair ClaI...

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Pubblicato in:J Clin Microbiol
Autori principali: Lefebvre, R B, Perng, G C, Johnson, R C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC268016/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2380391/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.28.7.1673-1675.1990
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