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In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial Antigen Presenting Cells (aAPC)

Adoptive immunotherapy for treatment of cancers and infectious diseases is often hampered by a high degree of variability in the final T cell product and the limited in vivo function and survival of ex vivo expanded antigen-specific cytotoxic T cells (CTL). This has stimulated interest in developmen...

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Main Authors: Durai, Malarvizhi, Krueger, Christine, Ye, Zhaohui, Cheng, Linzhao, Mackensen, Andreas, Oelke, Mathias, Schneck, Jonathan P
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680120/
https://ncbi.nlm.nih.gov/pubmed/18563409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0542-1
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