An integrin-α4–14-3-3ζ–paxillin ternary complex mediates localised Cdc42 activity and accelerates cell migration

α4 integrins are used by leukocytes and neural crest derivatives for adhesion and migration during embryogenesis, immune responses and tumour invasion. The pro-migratory activity of α4 integrin is mediated in part through the direct binding of the cytoplasmic domain to paxillin. Here, using intermol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Deakin, Nicholas O., Bass, Mark D., Warwood, Stacey, Schoelermann, Julia, Mostafavi-Pour, Zohreh, Knight, David, Ballestrem, Christoph, Humphries, Martin J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Company of Biologists 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680104/
https://ncbi.nlm.nih.gov/pubmed/19401330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.049130
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